@charset "UTF-8";
/*=============================================*/
/*Font import */
/*=============================================*/
@import url(https://fonts.googleapis.com/css2?family=Oswald:wght@200;300;400;500;600&display=swap);
@import url(https://use.fontawesome.com/releases/v5.10.2/css/all.css);
@import url(https://site-assets.fontawesome.com/releases/v6.2.0/css/all.css);
@import url(https://fonts.googleapis.com/css2?family=Noto+Sans+JP:wght@400;500;700;900&display=swap);
/*=============================================*/
/*Reset CSS*/
/*=============================================*/
article, aside, aside, canvas, details, figcaption, figure, footer, header, hgroup, menu, nav, section, summary, main {
    display: block;
}

blockquote, body, dd, div, dl, dt, fieldset, figure, form, h1, h2, h3, h4, h5, h6, input, li, ol, p, pre, td, textarea, th, ul {
    margin: 0;
    padding: 0;
    font-weight: normal;
}

table {
    border-collapse: collapse;
    border-spacing: 0;
}

li {
    list-style: none;
}

a,
a:link {
    text-decoration: none;
}

img {
    max-width: 100%;
    height: auto;
    border: 0;
    height: auto;
    vertical-align: bottom;
    backface-visibility: hidden;
    -webkit-backface-visibility: hidden;
}

button, input, select, textarea {
    margin: 0;
    padding: 0;
    background: none;
    border: none;
    border-radius: 0;
    outline: none;
    -webkit-appearance: none;
    -moz-appearance: none;
    appearance: none;
}

select::-ms-expand {
    display: none;
}

input[type="radio"]::-ms-check,
input[type="checkbox"]::-ms-check {
    display: none;
}

i {
    font-style: normal;
}

textarea {
    resize: none;
    font-family: sans-serif;
}

* {
    box-sizing: border-box;
}

/*=============================================*/
/*Common Base*/
/*=============================================*/
html {
    font-size: 62.5%;
    overflow: auto;
}

body {
    margin: auto;
    width: auto;
    font-family: 'Noto Sans JP', "Yu Gothic Medium", "游ゴシック Medium", YuGothic, "游ゴシック体", "ヒラギノ角ゴ Pro W3", "メイリオ", sans-serif;
    -webkit-text-size-adjust: 100%;
    -moz-text-size-adjust: 100%;
    -ms-text-size-adjust: 100%;
    -o-text-size-adjust: 100%;
    text-size-adjust: 100%;
    -moz-osx-font-smoothing: grayscale;
    text-rendering: optimizeLegibility;
    overflow-x: hidden;
}

a, b, dd, dt, li, p, span, td, th {
    font-size: 15px;
    font-size: 1.5rem;
    line-height: 1.2;
    color: #333;
}

h1, h2, h3, h4, h5, h6 {
    color: #333;
}

@media screen and (max-width: 768px) {
    .pc_only {
        display: none !important;
    }
}

@media print, screen and (min-width: 769px) {
    .sp_only {
        display: none !important;
    }
}

.center {
    margin: auto;
    text-align: center;
    line-height: 180%;
}

.clearfix::after {
    content: "";
    display: block;
    clear: both;
}

.txt_base p {
    letter-spacing: 0.1em;
    line-height: 2.3;
}

.txt_base p:not(:last-child) {
    margin-bottom: 1.5em;
}

.txt_base p a {
    text-decoration: underline;
    color: #0052B0;
}

.txt_base.fs14 p {
    font-size: 1.4rem;
}

.mb20 {
    margin-bottom: 20px;
}

.mb30 {
    margin-bottom: 30px;
}

.mb40 {
    margin-bottom: 40px;
}

.mb50 {
    margin-bottom: 50px;
}

.mb60 {
    margin-bottom: 60px;
}

.tel_link,
.tel_link a {
    color: inherit;
    font-size: 1em;
}

a {
    word-break: break-all;
}

/*=============================================*/
/*  layout  Base                        */
/*=============================================*/
.main_width {
    width: calc(100% - 30px);
    max-width: 1100px;
    margin: auto;
}

.main_width.size1215 {
    max-width: 1215px;
}

.main_width.size800 {
    max-width: 800px;
}

section {
    padding: 80px 0;
}

/*=============================================*/
/*  layout                               */
/*=============================================*/
/********************************************/
/*header */
/********************************************/
.header {
    padding-top: 10px;
    background-color: #fff;
}

.header .header_top {
    margin-bottom: 15px;
}

.header .header_top p {
    color: #100964;
    font-size: 1.3rem;
    font-weight: 500;
}

.header .header_bottom {
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    -webkit-box-pack: justify;
    -ms-flex-pack: justify;
    justify-content: space-between;
    align-items: center;
    padding-bottom: 30px;
}

.header .logo {
    width: 20%;
    max-width: 170px;
    margin-right: 10%;
}

.header .right {
    width: 78%;
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    -webkit-box-pack: justify;
    -ms-flex-pack: justify;
    justify-content: space-between;
    align-items: flex-end;
}

.header .header_btn_list {
    width: 70%;
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
}

.header .header_btn_list li {
    width: 48%;
    max-width: 240px;
}

.header .header_btn_list li:not(:last-child) {
    margin-right: 4%;
}

.header .btn {
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    -webkit-box-pack: justify;
    -ms-flex-pack: justify;
    justify-content: space-between;
    text-align: center;
}

.header .btn li:not(:last-child) {
    margin-right: 20px;
}

.header .btn i {
    display: block;
    position: relative;
    z-index: 2;
}

.header .btn i:after {
    position: absolute;
    top: 50%;
    left: 50%;
    content: "";
    width: 30px;
    height: 30px;
    background: url(../img/common/bg-circle.svg) no-repeat center/cover;
    -webkit-transform: translate(-50%, -50%);
    -ms-transform: translate(-50%, -50%);
    transform: translate(-50%, -50%);
    z-index: -1;
}

.header .btn span {
    display: block;
    margin-top: 0.5em;
    line-height: 1;
    color: #0052B0;
    font-weight: 500;
}

.header .btn li a {
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.header .btn li a:hover {
    opacity: 0.7;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.header_btn a {
    display: block;
    padding: 0.7em 1em;
    border-radius: 50px;
    text-align: center;
    color: #fff;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.header_btn a span {
    font-weight: 500;
}

.header_btn a:hover {
    opacity: 0.7;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.header_btn.blue a {
    background: #0052B0;
}

.header_btn.light_blue a {
    background: #4187D8;
}

.main_nav {
    border-top: solid 1px #ccc;
    border-bottom: solid 1px #ccc;
}

.nav_list {
    max-width: 970px;
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    -webkit-box-pack: justify;
    -ms-flex-pack: justify;
    justify-content: space-between;
}

.nav_list li a {
    position: relative;
    display: block;
    font-size: 1.4rem;
    font-weight: 500;
    letter-spacing: 0.1em;
    padding: 1.4em 0.8em;
    text-align: center;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.nav_list li a:after {
    position: absolute;
    bottom: 0;
    left: 0;
    content: '';
    width: 0;
    height: 2px;
    background: #0052B0;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.nav_list li a:hover {
    color: #0052B0;
}

.nav_list li a:hover:after {
    width: 100%;
}

/********************************************/
/*  Sp-menu*/
/********************************************/
.sp_menu_trigger,
.sp_nav {
    display: none;
}

/********************************************/
/* main_visual */
/********************************************/
.main_visual {
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    -ms-flex-wrap: wrap;
    -webkit-flex-wrap: wrap;
    flex-wrap: wrap;
}

.main_visual .left,
.main_visual .right {
    position: relative;
    width: 50%;
}

.main_visual .left .inner,
.main_visual .right .inner {
    position: absolute;
    top: 50%;
    left: 3%;
    width: 94%;
    text-align: center;
    -webkit-transform: translateY(-50%);
    -ms-transform: translateY(-50%);
    transform: translateY(-50%);
    z-index: 2;
}

.main_visual .left:before,
.main_visual .right:before {
    position: absolute;
    top: 0;
    left: 0;
    content: "";
    width: 100%;
    height: 100%;
    z-index: 2;
}

.main_visual .left:before {
    background: rgba(160, 169, 240, 0.5);
}

.main_visual .right:before {
    background: rgba(160, 195, 237, 0.5);
}

.main_visual .ttl {
    margin-bottom: 30px;
    letter-spacing: 0.1em;
    color: #fff;
    font-size: 3.5rem;
    font-weight: 700;
}

.main_visual .ttl:first-letter {
    font-size: 1.8em;
}

.main_visual .logo {
    margin-bottom: 50px;
}

#top_main .main_slide_zoom {
    overflow: hidden;
}

@keyframes zoom-in {
    0% {
        transform: scale(1);
    }
    100% {
        transform: scale(1.2);
    }
}

#top_main .main_slide_zoom .swiper-slide-active img,
#top_main .main_slide_zoom .swiper-slide-duplicate-active img,
#top_main .main_slide_zoom .swiper-slide-prev img {
    animation: zoom-in 10s linear 0s 1 normal both;
}

.main_visual .all_space_link {
    position: absolute;
    top: 0;
    left: 0;
    display: block;
    width: 100%;
    height: 100%;
    z-index: 2;
}

.bottom_block .all_space_link .slide_btn,
.main_visual .all_space_link .slide_btn {
    position: relative;
    display: block;
    width: 300px;
    margin: auto;
    border-radius: 50px;
    text-align: center;
    overflow: hidden;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
    border: 1px solid #fff;
    font-family: 'Noto Sans JP', sans-serif;
    font-weight: 500;
}

.bottom_block .all_space_link .slide_btn span,
.main_visual .all_space_link .slide_btn span {
    display: inline-block;
    position: relative;
    z-index: 2;
    padding: 1.34em 1em;
    color: #fff;
}

.bottom_block .all_space_link .slide_btn span.en,
.main_visual .all_space_link .slide_btn span.en {
    padding: 0.6em 1em;
    letter-spacing: 0.03em;
    font-size: 2.5rem;
    font-family: 'Oswald', sans-serif;
    font-weight: 300;
}

.bottom_block .all_space_link .slide_btn:after,
.main_visual .all_space_link .slide_btn:after {
    position: absolute;
    top: 0;
    right: 240px;
    content: "";
    width: 100%;
    height: 100%;
    background: #0052B0;
    border-radius: 50px;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.bottom_block .all_space_link .slide_btn.search_btn b span,
.main_visual .all_space_link .slide_btn.search_btn b span {
    display: inline-block;
    position: relative;
    vertical-align: middle;
    letter-spacing: 0.1em;
}

.bottom_block .all_space_link .slide_btn.search_btn b span:after,
.main_visual .all_space_link .slide_btn.search_btn b span:after {
    display: inline-block;
    content: "";
    width: 18px;
    height: 18px;
    margin-left: 0.5em;
    background: url(../img/common/ico-glass.svg) no-repeat center/contain;
    vertical-align: middle;
}

.bottom_block .all_space_link:hover .slide_btn:after,
.main_visual .all_space_link:hover .slide_btn:after {
    right: 0;
}

.bottom_block .all_space_link .slide_btn.navy:after {
    background: #100964;
}

/********************************************/
/* top_about_block */
/********************************************/
.top_about_block .main_width {
    max-width: 870px;
}

.top_about_block .center_ttl .en {
    color: #000;
}

.top_about_block .big_ttl {
    line-height: 1.8;
    color: #100964;
    font-size: 2.5rem;
    font-weight: 700;
}

/********************************************/
/* top_service_block */
/********************************************/
.top_service_block .service_list li:not(:last-child) {
    margin-bottom: 60px;
}

.top_service_block .service_list .flexbox {
    margin-bottom: 20px;
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    -ms-flex-wrap: wrap;
    -webkit-flex-wrap: wrap;
    flex-wrap: wrap;
}

.top_service_block .service_list .flexbox .left {
    width: 47%;
    padding: 30px;
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    -webkit-box-align: center;
    -ms-flex-align: center;
    align-items: center;
}

.top_service_block .service_list .flexbox .left p {
    letter-spacing: 0.1em;
    color: #fff;
    font-size: 4.5rem;
    font-weight: 700;
}

.top_service_block .service_list .flexbox .right {
    width: 53%;
}

/********************************************/
/* top_partnership_block */
/********************************************/
.partnership_slider {
    position: relative;
}

.partnership_slider .swiper-wrapper, .partnership_slider .swiper {
    position: unset;
}

.partnership_slider .swiper-button-prev,
.partnership_slider .swiper-button-next {
    width: auto;
}

.partnership_slider .swiper-button-prev:after,
.partnership_slider .swiper-button-next:after {
    width: 36px;
    height: 36px;
    content: "";
    background: url(../img/common/ico-arr-left.svg) no-repeat center/contain;
}

.partnership_slider .swiper-button-prev {
    left: -45px;
}

.partnership_slider .swiper-button-next {
    right: -45px;
}

.partnership_slider .swiper-button-next:after {
    transform: scale(-1, 1);
}

.partnership_slider .swiper-pagination {
    bottom: -50px;
}

/********************************************/
/* bottom_block */
/********************************************/
.bottom_block {
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    -ms-flex-wrap: wrap;
    -webkit-flex-wrap: wrap;
    flex-wrap: wrap;
}

.bottom_block .left,
.bottom_block .right {
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    -webkit-box-pack: center;
    -ms-flex-pack: center;
    justify-content: center;
    -webkit-box-align: center;
    -ms-flex-align: center;
    align-items: center;
    width: 50%;
    padding: 60px 0 40px;
}

.bottom_block .left p,
.bottom_block .right p {
    margin-bottom: 1em;
    letter-spacing: 0.1em;
    color: #fff;
    text-align: center;
    font-size: 2.3rem;
    font-weight: 700;
}

.bottom_block .left .logo,
.bottom_block .right .logo {
    margin-bottom: 40px;
}

.bottom_block .left,
.bottom_block .right {
    position: relative;
    padding: 0;
}

.bottom_block .all_space_link {
    display: block;
    width: 100%;
    padding: 60px 0 40px;
    text-align: center;
}

/********************************************/
/* contact_bottom_block */
/********************************************/
.contact_bottom_block {
    padding: 80px 0;
    position: relative;
    background: url(../img/common/contact-bg.jpg) no-repeat center/cover;
}

.contact_bottom_block:after {
    position: absolute;
    top: 0;
    left: 0;
    content: "";
    width: 100%;
    height: 100%;
    background: rgba(16, 9, 100, 0.5);
}

.contact_bottom_block .main_width {
    position: relative;
    z-index: 2;
}

.contact_bottom_block .center_ttl .en {
    color: #fff;
}

.contact_bottom_block p {
    color: #fff;
}

.bottom_contact_list {
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    -webkit-box-pack: justify;
    -ms-flex-pack: justify;
    justify-content: space-between;
    -webkit-box-align: center;
    -ms-flex-align: center;
    align-items: center;
}

.bottom_contact_list li {
    width: 31%;
    color: #fff;
    text-align: center;
}

.bottom_contact_list li span,
.bottom_contact_list li p {
    color: inherit;
}

.bottom_contact_list li .sub_ttl {
    margin-bottom: 0.3em;
    padding: 0.3em 3em;
    display: inline-block;
    border-radius: 30px;
    border: solid 1px #fff;
    font-weight: 700;
}

.bottom_contact_list li .tel {
    display: block;
    margin-bottom: 0.2em;
    font-size: 2.5rem;
    font-family: 'Oswald', sans-serif;
    font-weight: 200;
}

.bottom_contact_list li .tel span {
    font-size: 2em;
}

.bottom_contact_list .border_btn a {
    display: block;
    padding: 1em;
    border-radius: 50px;
    text-align: center;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.bottom_contact_list .border_btn a span:after {
    position: relative;
    top: -0.1em;
    content: "";
    display: inline-block;
    width: 20px;
    height: 16px;
    margin-left: 1em;
    vertical-align: middle;
    background: url(../img/common/ico-mail.svg) no-repeat center/contain;
}

.bottom_contact_list .border_btn a:hover {
    background: #100964;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

/********************************************/
/* footer */
/********************************************/
.footer {
    padding: 30px 0;
}

.footer .footer_link {
    margin-bottom: 60px;
}

.footer .footer_link li {
    display: inline-block;
    margin-bottom: 0.4em;
    font-weight: 500;
}

.footer .footer_link li:not(:last-child):after {
    content: "/";
    margin: 0 10px;
}

.footer .footer_link li a {
    display: inline-block;
    padding: 0.2em;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.footer .footer_link li a:hover {
    color: #0052B0;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.footer .copyright {
    display: block;
    text-align: right;
    font-size: 1.6rem;
    font-family: 'Oswald', sans-serif;
    font-weight: 300;
}

/*=============================================*/
/* index-medical */
/*=============================================*/
.sub_main_visual {
    position: relative;
    padding: 60px 0;
    background: url(../img/top_medical/main-bg.jpg) no-repeat center/cover;
}

.sub_main_visual:before {
    position: absolute;
    top: 0;
    left: 0;
    content: "";
    width: 100%;
    height: 100%;
    background: #A0A9F0;
    mix-blend-mode: multiply;
}

.sub_main_visual .main_width {
    position: relative;
    z-index: 2;
}

.sub_main_visual .main_top {
    margin-bottom: 40px;
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    -webkit-box-pack: justify;
    -ms-flex-pack: justify;
    justify-content: space-between;
    -webkit-box-align: center;
    -ms-flex-align: center;
    align-items: center;
}

.sub_main_visual .main_top .logo {
    width: 40%;
}

.sub_main_visual .main_top .txt_base {
    width: 52%;
}

.sub_main_visual .main_top .txt_base p {
    letter-spacing: 0;
    color: #fff;
    font-size: 2.0rem;
    font-weight: 700;
}

.sub_main_visual .main_bottom {
    background: rgba(255, 255, 255, 0.8);
    padding: 30px 50px;
    border-radius: 16px;
}

.sub_main_visual .main_bottom .ttl {
    margin-bottom: 1.5em;
    text-align: center;
    letter-spacing: 0.1em;
    font-size: 1.8rem;
    font-weight: bold;
}

.sub_main_visual .main_bottom .search_list {
    width: 100%;
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    justify-content: space-between;
    margin-bottom: 38px;
}

.sub_main_visual .main_bottom .search_list li {
    width: 36%;
    max-width: 273px;
}

.sub_main_visual .main_bottom .search_list li:not(:nth-child(3n)) {
    margin-right: 2%;
}

.sub_main_visual .main_bottom .search_list li .name {
    font-size: 1.5rem;
    font-weight: bold;
    margin-bottom: 0.8em;
}

.sub_main_visual .main_bottom .search_list li select {
    width: 100%;
    padding: 1.23em 2.5em 1.23em 1em;
    background: url(../img/common/ico-down-arrow.svg) no-repeat center right 12px/14px, #fff;
    border-radius: 5px;
    font-size: 1.5rem;
}

.sub_main_visual .main_bottom .search_list li input[type=text] {
    width: 100%;
    padding: 1.23em 2.5em 1.23em 1em;
    background: #fff;
    border-radius: 5px;
    font-size: 1.5rem;
}

.sub_main_visual .main_bottom .search_btn {
    text-align: center;
}

.sub_main_visual .main_bottom .search_btn button,
.sub_main_visual .main_bottom .search_btn a {
    display: block;
    width: 100%;
    max-width: 298px;
    margin: 0 auto;
    padding: 0.6em 2em;
    background: #4187D8;
    border-radius: 100px;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.sub_main_visual .main_bottom .search_btn button span,
.sub_main_visual .main_bottom .search_btn a span {
    display: inline-block;
    position: relative;
    vertical-align: middle;
    letter-spacing: 0.1em;
    color: #fff;
}

.sub_main_visual .main_bottom .search_btn button:hover,
.sub_main_visual .main_bottom .search_btn a:hover {
    opacity: 0.7;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.top_pickup_block {
    padding: 50px 0 70px;
}

#pickup_slider .main_width.size1215 {
    width: calc(100% - 120px);
}

#pickup_slider .pickup_slider {
    position: relative;
    max-width: 1100px;
    margin: 0 auto;
}

#pickup_slider .pickup_slider .slick-prev,
#pickup_slider .pickup_slider .slick-next {
    position: absolute;
    top: 0;
    bottom: 0;
    content: '';
    margin: auto;
    width: 36px;
    height: 36px;
    background: url(../img/common/ico-arr-left.svg) no-repeat center/100%;
    z-index: 1;
    cursor: pointer;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

#pickup_slider .pickup_slider .slick-prev:before,
#pickup_slider .pickup_slider .slick-next:before {
    content: none;
}

#pickup_slider .pickup_slider .slick-prev:hover,
#pickup_slider .pickup_slider .slick-next:hover {
    opacity: 0.7;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

#pickup_slider .pickup_slider .slick-prev {
    left: -50px;
    transform: rotate(0deg);
}

#pickup_slider .pickup_slider .slick-next {
    right: -50px;
    transform: rotate(180deg);
}

#pickup_slider .pickup_slider {
    position: relative;
}

#pickup_slider .pickup_slider .slide_dots {
    position: absolute;
    bottom: -30px;
    left: 0;
    right: 0;
    text-align: center;
}

#pickup_slider .pickup_slider .slide_dots li {
    display: inline-block;
    margin-right: 25px;
}

#pickup_slider .pickup_slider .slide_dots li button {
    position: relative;
    text-indent: -9999px;
}

#pickup_slider .pickup_slider .slide_dots li button:before {
    position: absolute;
    bottom: 0;
    left: 0;
    right: 0;
    content: '';
    width: 12px;
    height: 12px;
    background: #E3E3E3;
    border-radius: 50px;
}

#pickup_slider .pickup_slider .slide_dots li.slick-active button::before {
    background: #4187D8;
}

#pickup_slider .pickup_slider .slick-track {
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
}

#pickup_slider .pickup_slider .slick-slide {
    padding: 0 12px;
    height: auto;
}

#pickup_slider .pickup_slider .slick-slide img {
    margin-bottom: 20px;
}

#pickup_slider .pickup_slider .slick-slide .ttl {
    font-size: 1.4rem;
    line-height: 1.8;
    letter-spacing: 0.1em;
}

#pickup_slider .pickup_slider .slick-slide a {
    display: block;
}

.top_tour_news_block {
    padding: 50px 0 65px;
}

.top_tour_news_block .left_ttl {
    margin-bottom: 30px;
}

.top_tour_news_block .left_ttl .en {
    margin-top: 0;
    margin-bottom: 0.2em;
    font-size: 4.4rem;
    font-weight: 400;
    line-height: 1.5;
    letter-spacing: 0.05em;
}

.top_tour_news_block .left_ttl .jp {
    font-size: 1.6rem;
    font-weight: bold;
    line-height: 1.4;
    letter-spacing: 0.1em;
}

.top_tour_news_block .left_ttl .jp:after {
    content: none;
}

.top_tour_news_block .wrapper {
    width: 100%;
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    justify-content: space-between;
}

.top_tour_news_block .wrapper .left {
    width: 20%;
    margin-right: 5%;
}

.top_tour_news_block .wrapper .right {
    width: 70%;
}

.top_tour_news_block .tour_news_list li:not(:last-child) {
    margin-bottom: 0.8em;
}

.top_tour_news_block .tour_news_list li a {
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    padding: 0.2em 0.1em;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.top_tour_news_block .tour_news_list li a .date {
    display: inline-block;
    margin-right: 2em;
    font-family: 'Oswald', sans-serif;
    font-weight: 300;
    font-size: 1.7rem;
    line-height: 1.5;
    color: #727272;
}

.top_tour_news_block .tour_news_list li a .ttl {
    font-size: 1.4rem;
    font-weight: 500;
    line-height: 1.7;
    letter-spacing: 0.1em;
    color: #4187D8;
    text-decoration: underline;
    text-underline-offset: 0.2em;
}

.top_tour_news_block .tour_news_list li a:hover {
    opacity: 0.7;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.top_category_block {
    padding: 50px 0 25px;
}

.top_category_block .center_ttl {
    margin-bottom: 0.7em;
    text-align: center;
}

.top_category_block .center_ttl span {
    position: relative;
    display: inline-block;
    padding: 0 1.8em;
    font-size: 3rem;
    font-weight: bold;
    line-height: 1.4;
    letter-spacing: 0.1em;
    color: #fff;
}

.top_category_block .center_ttl span:before, .top_category_block .center_ttl span:after {
    position: absolute;
    top: 0;
    bottom: 0;
    content: '';
    margin: auto;
    width: 30px;
    height: 3px;
    background: #fff;
}

.top_category_block .center_ttl span:before {
    left: 0;
}

.top_category_block .center_ttl span:after {
    right: 0;
}

.top_category_block .category_list {
    width: 100%;
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    -ms-flex-wrap: wrap;
    -webkit-flex-wrap: wrap;
    flex-wrap: wrap;
}

.top_category_block .category_list li {
    width: 23.5%;
    margin-bottom: 17px;
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    flex-direction: column;
}

.top_category_block .category_list li:not(:nth-child(4n)) {
    margin-right: 2%;
}

.top_category_block .category_list li a {
    position: relative;
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    flex-direction: column;
    flex-grow: 1;
    justify-content: center;
    padding: 1.04em 2em;
    background: #fff;
    background: -moz-linear-gradient(45deg, #fff 0%, #EAF2FC 100%);
    background: -webkit-linear-gradient(45deg, #fff 0%, #EAF2FC 100%);
    background: linear-gradient(45deg, #fff 0%, #EAF2FC 100%);
    filter: progid:DXImageTransform.Microsoft.gradient( startColorstr='#fff', endColorstr='#EAF2FC',GradientType=1 );
    border: 1px solid #D0D0D0;
    border-radius: 10px;
    font-size: 1.5rem;
    font-weight: 500;
    line-height: 1.6;
    letter-spacing: 0.1em;
    color: #100964;
    text-align: center;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.top_category_block .category_list li a:before {
    position: absolute;
    top: 0;
    right: 11px;
    bottom: 0;
    content: '';
    margin: auto;
    width: 7px;
    height: 7px;
    border-top: 2px solid #100964;
    border-right: 2px solid #100964;
    transform: rotate(45deg);
}

.top_category_block .category_list li a:hover {
    opacity: 0.7;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.top_conference_block {
    padding: 75px 0 65px;
}

.top_conference_block .border_ttl span {
    padding-left: 55px;
}

.top_conference_block .border_ttl span:before {
    position: absolute;
    top: 0;
    left: 3px;
    bottom: 0;
    content: '';
    margin: auto;
    width: 35px;
    height: 35px;
    background: url(../img/top_medical/ico-info.svg) no-repeat center/100%;
}

.top_conference_block .conference_list {
    margin-bottom: 40px;
}

.top_conference_block .conference_list li {
    width: 100%;
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    align-items: center;
    padding: 25px;
    border-bottom: 1px dotted #939393;
}

.top_conference_block .conference_list li .left {
    width: 59%;
    margin-right: 3%;
}

.top_conference_block .conference_list li .right {
    width: 38%;
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    align-items: center;
    justify-content: flex-end;
}

.top_conference_block .conference_list .top {
    width: 100%;
    display: -ms-flexbox;
    display: -webkit-box;
    display: -webkit-flex;
    display: flex;
    margin-bottom: 10px;
}

.top_conference_block .conference_list .top .category {
    display: inline-block;
    margin-right: 5%;
    padding: 0.04em 1.5em;
    border: 1px solid #0052B0;
    border-radius: 100px;
    font-size: 1.4rem;
    line-height: 1.6;
    letter-spacing: 0.1em;
    color: #0052B0;
    text-align: center;
}

.top_conference_block .conference_list .top .location {
    display: inline-block;
    font-size: 1.4rem;
    line-height: 1.6;
    letter-spacing: 0.1em;
    color: #939393;
}

.top_conference_block .conference_list .ttl {
    margin-bottom: 0.4em;
    font-size: 1.8rem;
    font-weight: 500;
    line-height: 1.6;
    letter-spacing: 0.1em;
}

.top_conference_block .conference_list .en_ttl {
    font-family: 'Oswald', sans-serif;
    font-weight: 500;
    font-size: 1.4rem;
    line-height: 1.5;
    letter-spacing: 0.1em;
    color: #939393;
}

.top_conference_block .conference_list dl.date {
    margin-bottom: 10px;
}

.top_conference_block .conference_list dl.date dt, .top_conference_block .conference_list dl.date dd {
    font-size: 1.3rem;
    color: #939393;
}

.top_conference_block .conference_list dl.date dt {
    width: 4.5em;
    float: left;
}

.top_conference_block .conference_list dl.date dd {
    padding-left: 5em;
}

.top_conference_block .conference_list li .right > .arrow_btn {
    width: 100%;
    max-width: 196px;
}

.top_conference_block .conference_list li .right > .arrow_btn:not(:last-of-type) {
    margin-right: 3%;
}

.top_conference_block .conference_list li .right > .arrow_btn.ver_ico a {
    padding: 0.9em 2.3em;
    background: #4187D8;
}

.top_conference_block .conference_list li .right > .arrow_btn.ver_ico a:before {
    width: 15px;
    height: 12px;
    background: url(../img/top_medical/ico-mail.svg) no-repeat center/100%;
    border-top: none;
    border-right: none;
    transform: rotate(0deg);
}

.top_conference_block .main_width > .arrow_btn {
    width: 100%;
    max-width: 298px;
    margin: 0 auto;
}

.top_conference_block .main_width > .arrow_btn a {
    padding: 1.17em 2em;
    font-size: 1.7rem;
}

.top_conference_block .main_width > .arrow_btn a:before {
    right: 19px;
    width: 8px;
    height: 8px;
}

.top_information_block {
    padding: 80px 0 110px;
}

.top_information_block .main_width {
    position: relative;
}

.top_information_block .main_width .arrow_btn {
    position: absolute;
    top: 0;
    right: 0;
    width: 100%;
    max-width: 213px;
}

.top_information_block .information_list li a {
    position: relative;
    display: block;
    padding: 15px 60px 15px 0;
    border-bottom: 1px dotted #939393;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

.top_information_block .information_list li a .top {
    margin-bottom: 10px;
}

.top_information_block .information_list li a .top .date {
    display: inline-block;
    margin-right: 3%;
    font-family: 'Oswald', sans-serif;
    font-weight: 500;
    font-size: 1.6rem;
    letter-spacing: 0.1em;
    color: #939393;
}

.top_information_block .information_list li a .top .category {
    display: inline-block;
    margin-right: 1em;
    font-size: 1.4rem;
    font-weight: 500;
    line-height: 1.5;
    letter-spacing: 0.1em;
    color: #939393;
}

.top_information_block .information_list li a .top .category:last-child {
    margin-right: 0;
}

.top_information_block .information_list li a .ttl {
    font-size: 1.7rem;
    font-weight: 500;
    line-height: 1.6;
    letter-spacing: 0.1em;
}

.top_information_block .information_list li a:before, .top_information_block .information_list li a:after {
    position: absolute;
    top: 0;
    bottom: 0;
    content: '';
    margin: auto;
}

.top_information_block .information_list li a:before {
    right: 10px;
    width: 32px;
    height: 32px;
    border: 1px solid #100964;
    border-radius: 100px;
}

.top_information_block .information_list li a:after {
    right: 25px;
    width: 6px;
    height: 6px;
    border-top: 1px solid #100964;
    border-right: 1px solid #100964;
    transform: rotate(45deg);
}

.top_information_block .information_list li a:hover {
    opacity: 0.7;
    -webkit-transition: all 0.3s;
    transition: all 0.3s;
}

/*=============================================*/
/* index-dental */
/*=============================================*/
.sub_main_visual.ver_dental {
    background: url(../img/top_dental/main-bg.jpg) no-repeat center/cover;
}

.sub_main_visual.ver_dental:before {
    background: #A0C3ED;
}

.top_category_block .category_list li {
    width: 32%;
}

.top_category_block .category_list li:not(:nth-child(4n)) {
    margin-right: 0;
}

.top_category_block .category_list li:not(:nth-child(3n)) {
    margin-right: 2%;
}

/*=============================================*/
/*media query    Tablet */
/*=============================================*/
@media screen and (max-width: 1024px) {
    /********************************************/
    /* main_visual */
    /********************************************/
    .main_visual .ttl {
        font-size: 3.0vw;
    }
    .main_visual .ttl:first-letter {
        font-size: 1.5em;
    }
    .main_visual .logo {
        width: 70%;
        margin: 0 auto 50px;
    }
    /********************************************/
    /* bottom_block */
    /********************************************/
    .bottom_block .left .logo,
    .bottom_block .right .logo {
        width: 70%;
        margin: 0 auto 40px;
    }
    /********************************************/
    /* contact_bottom_block */
    /********************************************/
    .bottom_contact_list li .tel {
        font-size: 2.7vw;
    }
    .bottom_contact_list li .tel span {
        font-size: 1.5em;
    }
}

/*=============================================*/
/*media query    Tablet ipad 5.7inch */
/*=============================================*/
@media screen and (max-width: 768px) {
    a, b, dd, dt, li, p, span, td, th {
        font-size: 14px;
        font-size: 1.4rem;
    }
    /*=============================================*/
    /*  layout  Base                        */
    /*=============================================*/
    section {
        padding: 60px 0;
    }
    /********************************************/
    /* body fixed*/
    /********************************************/
    body {
        width: 100%;
    }
    body.fixed {
        position: fixed;
        width: 100%;
    }
    /********************************************/
    /*header */
    /********************************************/
    .header .header_top {
        padding-right: 50px;
    }
    .header .header_top p {
        font-size: 1.1rem;
    }
    .header .header_bottom {
        display: block;
        padding-bottom: 10px;
    }
    .header .logo {
        width: 30%;
        margin-right: auto;
    }
    .header .header_btn_list {
        width: 100%;
        display: block;
        margin-bottom: 20px;
    }
    .header .header_btn_list li {
        width: 100%;
        max-width: none;
    }
    .header .header_btn_list li:not(:last-child) {
        margin: 0 auto 15px;
    }
    .header .btn {
        display: -ms-flexbox;
        display: -webkit-box;
        display: -webkit-flex;
        display: flex;
        -webkit-box-pack: justify;
        -ms-flex-pack: justify;
        justify-content: space-between;
        margin-bottom: 20px;
    }
    .header .btn li {
        width: 49%;
    }
    .header .btn li:not(:last-child) {
        margin-right: 20px;
    }
    .header .btn a {
        display: block;
        padding: 1em 0.5em;
        background: #fff;
        border: solid 1px #ccc;
        border-radius: 50px;
    }
    .header .btn i {
        display: inline-block;
        vertical-align: middle;
        margin-right: 0.5em;
    }
    .header .btn span {
        display: inline-block;
        margin-top: 0;
        vertical-align: middle;
    }
    .header_btn a {
        padding: 1em;
    }
    /********************************************/
    /*  Sp-menu btn*/
    /********************************************/
    .sp_menu_trigger,
    .sp_menu_trigger span {
        display: inline-block;
        transition: all .4s;
        box-sizing: border-box;
        cursor: pointer;
    }
    .sp_menu_trigger {
        position: fixed;
        top: 0;
        right: 0;
        width: 50px;
        height: 50px;
        background-color: #0052B0;
        z-index: 9999;
        -webkit-transition: all 0.3s;
        transition: all 0.3s;
    }
    .sp_menu_trigger span {
        position: absolute;
        background: #fff;
        width: 27px;
        height: 2px;
        left: 0;
        right: 0;
        margin: auto;
    }
    .sp_menu_trigger span:nth-of-type(1) {
        top: 15px;
    }
    .sp_menu_trigger span:nth-of-type(2) {
        top: 0;
        bottom: 0;
    }
    .sp_menu_trigger span:nth-of-type(3) {
        bottom: 15px;
    }
    .sp_menu_trigger.nogap {
        top: 0;
        right: 0;
    }
    .sp_menu_trigger.active span:nth-of-type(1) {
        -webkit-transform: translateY(9px) rotate(-315deg);
        transform: translateY(9px) rotate(-315deg);
    }
    .sp_menu_trigger.active span:nth-of-type(2) {
        opacity: 0;
    }
    .sp_menu_trigger.active span:nth-of-type(3) {
        -webkit-transform: translateY(-9px) rotate(315deg);
        transform: translateY(-9px) rotate(315deg);
    }
    /********************************************/
    /*  Sp-menu list*/
    /********************************************/
    header .main_nav {
        display: none;
        position: fixed;
        top: 0;
        left: 0;
        background-color: rgba(255, 255, 255, 0.9);
        width: 100vw;
        height: 100vh;
        -webkit-overflow-scrolling: touch;
        z-index: 9998;
        overflow-y: scroll;
        padding: 60px 20px 60px;
        box-sizing: border-box;
        text-align: left;
    }
    header .nav_list {
        display: block;
        border-top: solid 1px #ccc;
    }
    header .nav_list > li {
        display: block;
        padding: 0;
        border-bottom: solid 1px #ccc;
    }
    header .nav_list > li a {
        color: #100964;
    }
    .nav_list {
        width: 100%;
        overflow: hidden;
    }
    /********************************************/
    /* main_visual */
    /********************************************/
    .main_visual .left,
    .main_visual .right {
        width: 100%;
    }
    .main_visual .ttl {
        margin-bottom: 0.5em;
        font-size: 7vw;
    }
    .main_visual .logo {
        margin-bottom: 30px;
    }
    /********************************************/
    /* top_about_block */
    /********************************************/
    .top_about_block .big_ttl {
        font-size: 1.8rem;
    }
    /********************************************/
    /* top_service_block */
    /********************************************/
    .top_service_block .service_list .flexbox .left {
        width: 100%;
    }
    .top_service_block .service_list .flexbox .left p {
        font-size: 2.5rem;
    }
    .top_service_block .service_list .flexbox .right {
        width: 100%;
    }
    /********************************************/
    /* top_partnership_block */
    /********************************************/
    .partnership_slider {
        padding-left: 30px;
        padding-right: 30px;
    }
    .partnership_slider .swiper-button-prev:after,
    .partnership_slider .swiper-button-next:after {
        width: 30px;
        height: 30px;
    }
    .partnership_slider .swiper-button-prev {
        left: -10px;
    }
    .partnership_slider .swiper-button-next {
        right: -10px;
    }
    .partnership_slider .swiper-pagination {
        bottom: -30px;
    }
    /********************************************/
    /* bottom_block */
    /********************************************/
    .bottom_block .left,
    .bottom_block .right {
        width: 100%;
    }
    .bottom_block .left p,
    .bottom_block .right p {
        font-size: 2.0rem;
    }
    .bottom_block .all_space_link {
        padding: 60px 15px 40px;
    }
    /********************************************/
    /* contact_bottom_block */
    /********************************************/
    .contact_bottom_block {
        padding: 60px 0;
    }
    .bottom_contact_list {
        display: block;
    }
    .bottom_contact_list li {
        width: 90%;
        margin: auto;
    }
    .bottom_contact_list li:not(:last-child) {
        margin: 0 auto 25px;
    }
    .bottom_contact_list li .tel {
        font-size: 8.5vw;
    }
}

/*=============================================*/
/*media query    SmartPhone */
/*=============================================*/
@media screen and (max-width: 767px) {
    .txt_base p {
        letter-spacing: 0.1em;
        line-height: 2;
    }
    .txt_base p:not(:last-child) {
        margin-bottom: 1.5em;
    }
    .txt_base.fs14 p {
        font-size: 1.4rem;
        line-height: 1.9;
    }
    /*=============================================*/
    /*  layout  Base                        */
    /*=============================================*/
    section {
        padding: 45px 0;
    }
    /*=============================================*/
    /* index-medical */
    /*=============================================*/
    .sub_main_visual {
        padding: 50px 0;
    }
    .sub_main_visual .main_top {
        margin-bottom: 30px;
        display: block;
    }
    .sub_main_visual .main_top .logo {
        width: 100%;
        max-width: 280px;
        margin: 0 auto 20px;
    }
    .sub_main_visual .main_top .txt_base {
        width: 100%;
    }
    .sub_main_visual .main_top .txt_base p {
        font-size: 1.8rem;
        line-height: 2;
        text-align: center;
    }
    .sub_main_visual .main_bottom {
        padding: 30px;
        border-radius: 12px;
    }
    .sub_main_visual .main_bottom .search_list {
        display: block;
        margin-bottom: 25px;
    }
    .sub_main_visual .main_bottom .search_list li {
        width: 100%;
        max-width: 100%;
        margin: 0 auto;
    }
    .sub_main_visual .main_bottom .search_list li:not(:nth-child(3n)) {
        margin-right: auto;
        margin-bottom: 15px;
    }
    .sub_main_visual .main_bottom .search_list li .name {
        margin-bottom: 0.5em;
    }
    .sub_main_visual .main_bottom .search_list li select {
        background: url(../img/common/ico-down-arrow.svg) no-repeat center right 12px/12px, #fff;
    }
    .sub_main_visual .main_bottom .search_btn button,
    .sub_main_visual .main_bottom .search_btn a {
        padding: 1em 2em;
    }
    #pickup_slider .pickup_slider .slick-prev,
    #pickup_slider .pickup_slider .slick-next {
        width: 34px;
        height: 34px;
    }
    #pickup_slider .pickup_slider .slide_dots {
        bottom: -25px;
    }
    #pickup_slider .pickup_slider .slide_dots li {
        margin-right: 20px;
    }
    #pickup_slider .pickup_slider .slide_dots li button:before {
        width: 10px;
        height: 10px;
    }
    #pickup_slider .pickup_slider .slick-slide {
        padding: 0;
    }
    #pickup_slider .pickup_slider .slick-slide img {
        margin-bottom: 10px;
    }
    #pickup_slider .pickup_slider .slick-slide .ttl {
        font-size: 1.3rem;
        line-height: 1.5;
    }
    .top_tour_news_block {
        padding: 40px 0 50px;
    }
    .top_tour_news_block .left_ttl .en {
        font-size: 3.6rem;
        line-height: 1.2;
    }
    .top_tour_news_block .left_ttl .jp {
        font-size: 1.4rem;
    }
    .top_tour_news_block .wrapper {
        display: block;
    }
    .top_tour_news_block .wrapper .left {
        width: 100%;
        margin-right: 0%;
    }
    .top_tour_news_block .wrapper .right {
        width: 100%;
    }
    .top_tour_news_block .arrow_btn {
        width: 100%;
        max-width: 298px;
        margin: 0 auto;
    }
    .top_tour_news_block .tour_news_list {
        margin-bottom: 30px;
    }
    .top_tour_news_block .tour_news_list li a {
        padding: 0;
    }
    .top_tour_news_block .tour_news_list li a .date {
        font-size: 1.4rem;
    }
    .top_category_block {
        padding: 30px 0;
    }
    .top_category_block .center_ttl span {
        padding: 0 1.6em;
        font-size: 2.4rem;
    }
    .top_category_block .center_ttl span:before, .top_category_block .center_ttl span:after {
        width: 20px;
    }
    .top_category_block .category_list li {
        width: 49%;
        margin-bottom: 10px;
    }
    .top_category_block .category_list li:not(:nth-child(4n)) {
        margin-right: 0%;
    }
    .top_category_block .category_list li:not(:nth-child(2n)) {
        margin-right: 2%;
    }
    .top_category_block .category_list li a {
        padding: 0.8em 2em 0.8em 1em;
        border-radius: 6px;
        font-size: 1.4rem;
        text-align: left;
    }
    .top_category_block .category_list li a:before {
        right: 9px;
        width: 6px;
        height: 6px;
    }
    .top_conference_block {
        padding: 40px 0 45px;
    }
    .top_conference_block .border_ttl span {
        padding-left: 48px;
    }
    .top_conference_block .border_ttl span:before {
        width: 30px;
        height: 31px;
    }
    .top_conference_block .border_ttl {
        padding-left: 50px;
        text-indent: -50px;
    }
    .top_conference_block .conference_list {
        margin-bottom: 30px;
    }
    .top_conference_block .conference_list li {
        display: block;
        padding: 25px 10px;
    }
    .top_conference_block .conference_list li .left {
        width: 100%;
        margin-right: 0%;
        margin-bottom: 20px;
    }
    .top_conference_block .conference_list li .right {
        width: 100%;
        justify-content: flex-start;
    }
    .top_conference_block .conference_list .top .category {
        padding: 0.5em 1em;
        font-size: 1.3rem;
        line-height: 1.2;
    }
    .top_conference_block .conference_list .top .location {
        font-size: 1.3rem;
        line-height: 1.5;
    }
    .top_conference_block .conference_list .ttl {
        font-size: 1.5rem;
    }
    .top_conference_block .conference_list li .right > .arrow_btn {
        width: 100%;
    }
    .top_conference_block .conference_list li .right > .arrow_btn.ver_ico a {
        padding: 1.3em 2em;
    }
    .top_conference_block .main_width > .arrow_btn a {
        font-size: 1.6rem;
    }
    .top_conference_block .main_width > .arrow_btn a:before {
        width: 7px;
        height: 7px;
    }
    .top_information_block {
        padding: 50px 0 60px;
    }
    .top_information_block .main_width {
        position: relative;
    }
    .top_information_block .main_width .arrow_btn {
        position: relative;
        max-width: 240px;
        margin: 0 auto;
    }
    .top_information_block .main_width .information_list {
        margin-bottom: 30px;
    }
    .top_information_block .information_list li a {
        padding: 15px 60px 15px 0;
    }
    .top_information_block .information_list li a .top {
        margin-bottom: 5px;
    }
    .top_information_block .information_list li a .top .date {
        font-size: 1.3rem;
    }
    .top_information_block .information_list li a .ttl {
        font-size: 1.5rem;
    }
    /*=============================================*/
    /* index-dental */
    /*=============================================*/
    .top_category_block .category_list li {
        width: 48%;
    }
    .top_category_block .category_list li:not(:nth-child(3n)) {
        margin-right: 0%;
    }
    .top_category_block .category_list li:not(:nth-child(2n)) {
        margin-right: 2%;
    }
}